[Evaluation of the efficacy and tolerability of fluoxetine in major depression, Multicenter clinical study].

@article{Cabras1991EvaluationOT,
  title={[Evaluation of the efficacy and tolerability of fluoxetine in major depression, Multicenter clinical study].},
  author={Pier Luigi Cabras and E Enriques and Andrea Casini and Catherine Paoletti and P G Zagnoni},
  journal={Minerva psichiatrica},
  year={1991},
  volume={32 2},
  pages={93-101}
}
In an Italian multicenter study, 296 patients (115 males, 181 females) affected with major depression diagnosed according to the criteria of the DSM III-R, were treated for 8 weeks with 20 mg/die fluoxetine (Fluoxeren-Menarini s.r.l.). At the end of the therapy the mean scores on the Hamilton Depression Scale had improved considerably, going down from 27.42 to 10.05. 69.6% of the patients had improved by at least in the 50% in the HAM-D scores (responders). At the CGI the overall improvement… CONTINUE READING

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