[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture].

Abstract

Levofloxacin in vitro demonstrated bactericidal effect against susceptible and multi-drug resistant Mycobacterium tuberculosis: range of MICs was 0.25-0.5 mcg/mL, MBC-0.5-1.0 mcg/mL. Postantibiotic effect after 24-hour exposition to bactericidal concentrations was 35-39 days. Levofloxacin possesed low toxicity when tested in mice lungs tissue culture… (More)

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@article{Sokolova2002EvaluationOL, title={[Evaluation of levofloxacin antitubercular activity in vitro and in lung tissue culture].}, author={G. B. Sokolova and A D Kunichan and Konstantin Litovchenko and Alexander Tsybanev}, journal={Antibiotiki i khimioterapiia = Antibiotics and chemoterapy [sic]}, year={2002}, volume={47 12}, pages={15-9} }