[Establishment of a mouse model of ovarian oxidative stress].

  title={[Establishment of a mouse model of ovarian oxidative stress].},
  author={Xiaoning Wang and Changjun Zhang and Ying Zhang and Xue Ru and Qinqin Gong},
  journal={Nan fang yi ke da xue xue bao = Journal of Southern Medical University},
  volume={32 11},
OBJECTIVE To evaluate the feasibility of establishing a mouse model of ovarian oxidative stress by intraperitoneal injections of arsenic sodium. METHODS Twenty adult female Kunming mice were randomized equally into the normal control group and ovarian oxidative stress model group for intraperitoneal injections of 0.5 ml distilled water and 8 mg/kg arsenic sodium solution every other day, respectively. After 8 injections, the mice were sacrificed for histological observation of the ovarian… CONTINUE READING