[Establishment of Human Acute B-Lymphoblastic Leukemia--NOD/SCID Xenotransplant Mouse Model].

OBJECTIVE To establish human B-acute lymphoblastic leukemia NOD/SCID mouse model. METHODS The unirradiated mice aged 4-5 weeks were injected with Nalm-6 cells via the tail vein. Successful transplantation was assessed by the general state, bone marrow smear and histopathologic examination. RESULTS After 15 days of injection with Nalm-6 cells, the NOD… CONTINUE READING