[Epidermal growth factor-mediated NF-kappaB activation promotes uPA expression and invasiveness in pancreatic cancer cells].

Abstract

OBJECTIVE To determine the effect of EGF on the invasiveness of pancreatic cancer cells and its related regulatory mechanism. METHODS The effects of EGF on the proliferation, adhesion and invasion of pancreatic cancer cells were detected by WST-1 proliferation assay, adhesion assay and invasive assay. The expression of uPA was assayed by Western blot and… (More)

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@article{Zhang2007EpidermalGF, title={[Epidermal growth factor-mediated NF-kappaB activation promotes uPA expression and invasiveness in pancreatic cancer cells].}, author={Hao Zhang and Xiao-fang Liu and Yu-Ji Li and Jian-ping Zhou and Fan-Min Kong and Ming Dong}, journal={Zhonghua zhong liu za zhi [Chinese journal of oncology]}, year={2007}, volume={29 12}, pages={909-12} }