[Encephalopathy induced by fleroxacin in a patient with Machado-Joseph disease].

@article{Kimura1998EncephalopathyIB,
  title={[Encephalopathy induced by fleroxacin in a patient with Machado-Joseph disease].},
  author={Masahiko Kimura and Jiro Fujiyama and Asami Nagai and Masaaki Hirayama and Masaru Kuriyama},
  journal={Rinsho shinkeigaku = Clinical neurology},
  year={1998},
  volume={38 9},
  pages={846-8}
}
Convulsive seizure with unconciousness is an adverse effect of new quinolone antibiotics including fleroxacin. A block of GABA receptor in CNS has been reported as pathomechanism. A 48-year-old female patient with Machado-Joseph disease (MJD) had encephalopathy induced by fleroxacin. She revealed unconsciousness after the administration of fleroxacin (200mg… CONTINUE READING