Corpus ID: 41174230

[Emodin alleviates pulmonary fibrosis through inactivation of TGF-β1/ADAMTS-1 signaling pathway in rats].

@article{Liu2016EmodinAP,
  title={[Emodin alleviates pulmonary fibrosis through inactivation of TGF-β1/ADAMTS-1 signaling pathway in rats].},
  author={Lijing Liu and H. Qian and H. Xiao and Jianbin He and M. Xie and Zaiyan Wang and Xingyun Long},
  journal={Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology},
  year={2016},
  volume={32 10},
  pages={
          1342-1346
        }
}
  • Lijing Liu, H. Qian, +4 authors Xingyun Long
  • Published 2016
  • Medicine
  • Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
  • Objective To explore the role of transforming growth factor-β1 (TGF-β1)/a disintegrin-like and metalloproteinase with thrombospondin type 1 motif (ADAMTS-1) signaling pathway in emodin's anti-pulmonary fibrosis. Methods Sixty SD rats were randomly divided into 6 groups: normal control group, sham-operated group, model group, low-dose emodin intervention group (20 mg/kg), high-dose emodin intervention group (80 mg/kg) and prednisone group (5 mg/kg). Each group included 10 animals. Rats in the… CONTINUE READING
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