[Embryotoxicity and teratogenicity of derivatives of 1,3-indandion (author's transl)].

@article{Koehler1975EmbryotoxicityAT,
  title={[Embryotoxicity and teratogenicity of derivatives of 1,3-indandion (author's transl)].},
  author={Friedrich Koehler and K. Fickentscher and U Halfmann and H. D. Koch},
  journal={Archives of toxicology},
  year={1975},
  volume={33 3},
  pages={191-7}
}
The embryotoxicity and teratogenicity of 1,3-indandion and of 3 of its derivatives were proved. Pregnant SWS mice were given single i.p. injections on day 9 of gestation. A mixture of physiologic saline and TWEEN20 (3:1) was used as a solvent. The results refute the hypothesis of the action of thalidomide as an acylating agent responsible for the… CONTINUE READING