Corpus ID: 3471506

[Efficacy of secretin for the treatment of autism].

  title={[Efficacy of secretin for the treatment of autism].},
  author={Y. Toda and K. Mori and T. Hashimoto and M. Miyazaki and Y. Kuroda},
  journal={No to hattatsu = Brain and development},
  volume={36 4},
We administered secretin intravenously to 14 patients with autism (9 to 14 years, 10 males; 4 females), and evaluated its clinical effect. We also measured cerebrospinal fluid (CSF) levels of homovanillic acid (HVA) and 5-hydroxy-indole-3-acetic acid (5HIAA) before and after 4 weeks treatment, and compared them with the grade of improvement of the clinical symptoms assessed by the scores of Autism Diagnostic Interview-Revised (ADI-R). After injection of secretin, the ADI-R score increased in 8… Expand
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