[Effects of statins in cancer].

@article{MauricioCuello2013EffectsOS,
  title={[Effects of statins in cancer].},
  author={F MauricioCuello and C SumieKato and S DanielaD{\'i}az and Gareth Owen},
  journal={Revista medica de Chile},
  year={2013},
  volume={141 2},
  pages={
          227-36
        }
}
This review explores the evidence supporting a potential benefit of statins in cancer. In particular, the lipophilic forms (i.e. lovastatin, simvastatin, or similar) would have a therapeutic but not a preventive role. The pleiotropic effects that statins possess mainly explain this phenomenon, influencing the natural history of disease and the response to currently available therapies. By inhibiting the mevalonate pathway, statins would have a systemic effect, similar to that observed in… CONTINUE READING

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