[Effects of simvastatin on airway inflammation and airway mucus hypersecretion in rats with chronic obstructive pulmonary disease].

Abstract

OBJECTIVE To explore the preventive and therapeutic effects of simvastatin on rats with chronic obstructive pulmonary disease (COPD) and examine the mechanism of airway inflammation and airway mucus hypersecretion. METHODS The rat model of COPD was established by cigarette smoking and an intratracheal injection of lipopolysaccharide (LPS). A total of 18… (More)

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Cite this paper

@article{Wang2015EffectsOS, title={[Effects of simvastatin on airway inflammation and airway mucus hypersecretion in rats with chronic obstructive pulmonary disease].}, author={Sheng Wang and Lingling Xiong and Xue Deng and Wei Ren and Chundong Zhu and Chunying Li and Qun Zhou}, journal={Zhonghua yi xue za zhi}, year={2015}, volume={95 22}, pages={1726-30} }