[Effects of silicon dioxide on expression of alpha-smooth muscle actin in human lung fibroblasts].

@article{Hu2006EffectsOS,
  title={[Effects of silicon dioxide on expression of alpha-smooth muscle actin in human lung fibroblasts].},
  author={Yong-bin Hu and Qing-fu Zeng and Jin-wu Peng and Ling Chu and Xiang Li and Jin-sheng Wang and Hai-ying Jiang and Ji-fang Wen},
  journal={Zhonghua lao dong wei sheng zhi ye bing za zhi = Zhonghua laodong weisheng zhiyebing zazhi = Chinese journal of industrial hygiene and occupational diseases},
  year={2006},
  volume={24 9},
  pages={523-5}
}
OBJECTIVE To investigate the effects of SiO(2) on the expression of alpha-smooth muscle actin (alpha-SMA) in human lung fibroblasts in vitro and vivo. METHODS The experimental group comprised 32 rats while 32 rats were included in the control. In vivo, the expression of alpha-SMA in lung tissues of rats exposed to SiO(2), the supernate of RAW264.7 cells, SiO(2) and the growth factor beta(1) (TGF-beta(1)) were investigated, respectively. RESULTS (1) alpha-SMA positive myofibroblasts appeared… CONTINUE READING
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