Corpus ID: 25616074

[Effects of lipoic acid on cytokines and chemokines in astrocytes stimulated with lipopolysaccharide].

@article{Meng2014EffectsOL,
  title={[Effects of lipoic acid on cytokines and chemokines in astrocytes stimulated with lipopolysaccharide].},
  author={Jian Meng and M. Guo and J. Yu and Yan-hua Li and Chun-yun Liu and Shao-wei Hou and L. Feng and W. Yang and Junlian Li and Q. Feng and B. Xiao and Cungen Ma},
  journal={Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology},
  year={2014},
  volume={30 4},
  pages={
          346-50
        }
}
  • Jian Meng, M. Guo, +9 authors Cungen Ma
  • Published 2014
  • Chemistry, Medicine
  • Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology
OBJECTIVE To investigate the effects of lipoic acid (LA) on the release of TNF-α, IL-1β, IL-6, IL-10 and the expressions of chemokines in astrocytes stimulated with lipopolysaccharide (LPS). METHODS Astrocytes were separated from the cerebral cortex of newly-born C57BL/6 mice (within 48 h after birth). After identification and purification, the second-generation astrocytes were stimulated with LPS (1 μg/mL), and then treated with LA (100 μg/mL). The production of nitric oxide (NO) was assayed… Expand