[Effects of lidamycin on apoptotic gene expressions and cytoskeleton in human hepatoma bel-7402 cells].

Abstract

BACKGROUND & OBJECTIVE Lidamycin, one of enediyne antitumor antibiotics, was isolated by our institute. It is the focus of intense due to its unique chemical structure and potent cytotoxicities to tumor cells in vivo and in vitro. In addition to cleavage of DNA, effect of lidamycin on apoptotic gene expressions and cytoskeleton may involve in its high… (More)

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