[Effects of isosorbide dinitrate on coronary and systemic circulation in children].

@article{Hamaoka1991EffectsOI,
  title={[Effects of isosorbide dinitrate on coronary and systemic circulation in children].},
  author={Kenji Hamaoka and Kazuyuki Sakata and Y Omochi and Yoshinobu Kamiya and Zenshiro Onouchi},
  journal={Kokyu to junkan. Respiration & circulation},
  year={1991},
  volume={39 6},
  pages={595-600}
}
The effects of isosorbide dinitrate (ISDN) on the coronary and systemic circulation were evaluated in 8 children with angiographically normal coronary arteries. ISDN, 100 micrograms/kg, was given as a intracoronary injection. The pulmonary artery pressure, pulmonary capillary wedge pressure and left ventricular end diastolic pressure which are related to the pre-load were significantly reduced 1 min after the ISDN injection. The systolic blood pressure was reduced, and heart rate increased. The… CONTINUE READING

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