[Effects of icariin and icariside II on eNOS expression and NOS activity in porcine aorta endothelial cells].

@article{Liu2011EffectsOI,
  title={[Effects of icariin and icariside II on eNOS expression and NOS activity in porcine aorta endothelial cells].},
  author={Tao Liu and Xin-cheng Qin and Wei-ren Li and Feng Zhou and Guang-yong Li and Hua Xin and Yan-qing Gong and Zhong-cheng Xin},
  journal={Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences},
  year={2011},
  volume={43 4},
  pages={
          500-4
        }
}
OBJECTIVE To investigate the effects of icariin and icariside II on eNOS expression and NOS activity in endothelial cells and possible mechanisms using EGFR over-expressed porcine aorta endothelial (PAE) cell line. METHODS The EGFR gene was transfected into PAE cells and genetic stable cell line (PAE-EGFR) was selected. 12.5 μmol/L of icariin and of icariside II were used to treat the PAE and PAE-EGFR cells respectively for 48 h, the eNOS expression in each group was observed. EGF was also… CONTINUE READING

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