Corpus ID: 24300777

[Effects of heparin on the growth, extracellular matrix and matrix metalloproteinase gene expression in rat hepatic stellate cells].

@article{Li2000EffectsOH,
  title={[Effects of heparin on the growth, extracellular matrix and matrix metalloproteinase gene expression in rat hepatic stellate cells].},
  author={W. Li and J. Zhang and G. Huang and H. Zhu and X. Zhang and Y. Zhang},
  journal={Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology},
  year={2000},
  volume={8 4},
  pages={
          200-2
        }
}
  • W. Li, J. Zhang, +3 authors Y. Zhang
  • Published 2000
  • Biology, Medicine
  • Zhonghua gan zang bing za zhi = Zhonghua ganzangbing zazhi = Chinese journal of hepatology
OBJECTIVE To study the effects of heparin on the growth, extracellular matrix and matrix metalloproteinase (MMP) gene expression in rat hepatic stellate cells (HSC). METHODS Activated HSC was treated by heparin or fetal calf serum without heparin. The cell growth was evaluated by actual cell count and BrdU-labelled immunocytochemical stain. The gene expressions of type I and IV procollagen, fibronectin, MMP-2 and membrane type matrix metalloproteinase (MT-MMP) were investigated by… Expand
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