[Effects of gonadotropin releasing hormone analogues on chemotherapy-induced ovarian function damage in rats].

@article{Peng2007EffectsOG,
  title={[Effects of gonadotropin releasing hormone analogues on chemotherapy-induced ovarian function damage in rats].},
  author={Ping Peng and Dong-zi Yang and Cheng-yu Zheng and Ya-qin Mo and Ying-ming He and Qing-xue Zhang},
  journal={Zhonghua fu chan ke za zhi},
  year={2007},
  volume={42 8},
  pages={546-50}
}
OBJECTIVE To investigate the effects of gonadotropin releasing hormone agonist (GnRH-a) and antagonist (GnRH-ant) on cyclophosphamide (CTX)-induced ovarian damage in rats. METHODS Seventy-two Sprague-Dawley female rats were divided randomly into six groups, which received normal saline (NS), CTX, GnRH-a + NS, GnRH-a + CTX, GnRH-ant + NS, and GnRH-ant + CTX respectively. Levels of serum follicle-stimulating hormone (FSH), luteinizing hormone (LH) and estradiol (E(2)) were measured successively… CONTINUE READING