[Effects of cyclooxygenase-2 selective inhibitor celecoxib on the expression of major vault protein in rats with status epilepticus].

@article{Song2016EffectsOC,
  title={[Effects of cyclooxygenase-2 selective inhibitor celecoxib on the expression of major vault protein in rats with status epilepticus].},
  author={Ting-ting Song and Dan Li and Shao-ping Huang and Lin Yang and Xue-ying Wang and Yong-Sheng Jiang and Yu Peng Liu},
  journal={Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics},
  year={2016},
  volume={18 5},
  pages={440-5}
}
OBJECTIVE To study the effect of cyclooxygenase -2 selective inhibitor celecoxib on the expression of major vault protein ( MVP) in the brain of rats with status epilepticus and its possible roles in the treatment of refractory epilepsy. METHODS Sixty adult male Sprague-Dawley rats were randomly assigned to blank control (n=16), epilepsy model (n=22) and celecoxib treatment groups (n=22). After the status epilepticus was induced in rats by injecting lithium and pilocarpine, each group had 16… CONTINUE READING