• Corpus ID: 9097187

[Effects of beta-carotene and vitamin C on the expression of c-myc in human leukemic cell].

@article{Zhang2001EffectsOB,
  title={[Effects of beta-carotene and vitamin C on the expression of c-myc in human leukemic cell].},
  author={Jianguo Zhang and Jin-liang Zhang and Y. Zhao and H. Shi},
  journal={Wei sheng yan jiu = Journal of hygiene research},
  year={2001},
  volume={30 3},
  pages={
          160-2
        }
}
  • J. Zhang, J. Zhang, +1 author H. Shi
  • Published 1 May 2001
  • Chemistry, Medicine
  • Wei sheng yan jiu = Journal of hygiene research
In order to study the effects of beta-carotene and vitamin C(VC) on the expression of c-myc oncogene in human leukemic cell, myelogenous leukemic cell line HL-60 was cultured in vitro with standard methods. Trypan blue exclusion test and Northern blotting hybridization were used to detect the cell proliferation and the expression of c-myc gene. The results showed that the proliferation of HL-60 cell was inhibited after exposed to VC(5, 10, 100 mumol/L) and the occurrence of proliferation was… 
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