[Effects of basic fibroblast growth factor on growth of human periodontal ligament cells].

@article{Zhang2001EffectsOB,
  title={[Effects of basic fibroblast growth factor on growth of human periodontal ligament cells].},
  author={Shao-mei Zhang and Yiz Heng Liang and Pishan Yang},
  journal={Shanghai kou qiang yi xue = Shanghai journal of stomatology},
  year={2001},
  volume={10 2},
  pages={135-7}
}
OBJECTIVE To evaluate the biological effects of basic fibroblast growth factor (bFGF) on proliferation and DNA synthesis of periodontal ligament cells(PDLC). METHODS PDLC was isolated from periodontal ligament explants. The effects of bFGF on PDLC were assayed by MTT and 3(H)-TdR incorporation studies. The results were expressed as A value and CPM. Analysis of variance was used. RESULTS bFGF could enhance the proliferation and DNA synthesis of PDLC in a dose dependent manner. No inhibition… CONTINUE READING

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