[Effects of aging on insulin resistance and fat accumulation].

  title={[Effects of aging on insulin resistance and fat accumulation].},
  author={Takeshi Ohara},
  journal={Nihon rinsho. Japanese journal of clinical medicine},
  volume={64 1},
  • Takeshi Ohara
  • Published 2006 in
    Nihon rinsho. Japanese journal of clinical…
Insulin resistance is a major factor in the pathogenesis of type 2 diabetes and a risk factor for cardiovascular disease. Although the relationship between aging and insulin resistance has been well shown, precise mechanism of age-related insulin resistance still remain unknown. Insulin action may deteriorate with age mediated through accumulation of abdominal fat rather than aging per se. Recently it has been reported that intramyocellular lipid content and hepatic lipid content which are… CONTINUE READING