[Effects of HLA disparity of two umbilical cord blood units on human engraftment in SCID mice].

Abstract

OBJECTIVE To evaluate the feasibility and characteristics of human engraftment in HLA disparate cord blood transplantation. METHODS Two human HLA-haploidentical or HLA-mismatched cord blood units were transplanted into sublethally irradiated severe combined immunodeficiency (SCID) mice. The characteristics of engraftment, hematopoietic and immunological… (More)

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