[Effects of Epstein-Barr virus on host gene expression in Burkitt's lymphoma cell lines].

Abstract

BACKGROUND AND OBJECTIVE Epstein-Barr virus (EBV) is present in Burkitt's lymphoma (BL) cells in a latent form, showing a highly restricted pattern of gene expression with few tumor cells undergoing viral lytic replication. BL cell lines can be induced to enter the viral lytic cycle and initiate replication by stimulating surface immunoglobulin molecules… (More)

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