[Effect of vincristine on Mg2+-ATPase activity of actomyosin-like protein from sarcoma-45 and actomyosin from rat skeletal muscle].


Kinetic parameters of the inhibitory effect of vincristine on Mg2+ATPase activity containing in the actomyosin-like protein from rat sarcoma 45 and in actomyosin from rat skeletal muscle was studied. The alkaloid decreased the VM value for the reaction catalyzed by ATPase in presence of Mg2+ and EGTA and did not alter Km value for both contractile proteins… (More)


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