Corpus ID: 21145607

[Effect of tinofedrine on oxygen, glucose and lactate metabolism in dogs and rats].

@article{Thjemer1981EffectOT,
  title={[Effect of tinofedrine on oxygen, glucose and lactate metabolism in dogs and rats].},
  author={K. Thjemer and K. Obermeier},
  journal={Arzneimittel-Forschung},
  year={1981},
  volume={31 4},
  pages={
          693-700
        }
}
(+)-(R)-alpha(S)-1-[(3-3-Di-3-thienylallyl) amino]-ethyl-benzyl alcohol hydrochloride (tinofedrine hydrochloride) is a newly synthetized hemodynamic and cerebrally active substance. The results were obtained with dogs by synchronous measurement of vertebral and local cerebral blood flow, and assessment of O2, glucose and lactate metabolisms, In rats the cerebral glucose uptake index was taken as a scale for the glucose extraction. With dogs i.v. administration of tinofedrine causes, besides a… Expand