Corpus ID: 28335269

[Effect of thymosin alpha1 on immunological function and metabolism in peritoneal sepsis rats].

@article{Jiang2004EffectOT,
  title={[Effect of thymosin alpha1 on immunological function and metabolism in peritoneal sepsis rats].},
  author={Jun Jiang and Ning Li and Jie-shou Li},
  journal={Zhonghua wai ke za zhi [Chinese journal of surgery]},
  year={2004},
  volume={42 22},
  pages={
          1377-80
        }
}
  • Jun Jiang, Ning Li, J. Li
  • Published 22 November 2004
  • Medicine
  • Zhonghua wai ke za zhi [Chinese journal of surgery]
OBJECTIVE To investigate the effect of thymosin alpha1 on immunological function and protein metabolism in peritoneal sepsis rats. METHODS We observed the effect of thymosin alpha1 on T cell subclassification, TNFalpha, IL-6, IL-10, albumin, C-reactive protein (CRP) and mortality in cecal ligation and puncture (CLP) induced septic rats. RESULTS Concentration of TNFalpha and IL-6 in CLP induced septic rats increased significantly, and concentration of IL-10 decreased significantly compared… Expand
Thymus hormones as prospective anti-inflammatory agents
TLDR
Thymic hormones could be suitable as therapeutic agents for inflammation, mediated through thymic hormone effects on peripheral immune cell activities and bidirectional coupling between thymi hormones and the hypothalamic–pituitary–adrenal axis. Expand