[Effect of pioglitazone on the expression of TLR4 in renal tissue of diabetic rats].

@article{Yu2014EffectOP,
  title={[Effect of pioglitazone on the expression of TLR4 in renal tissue of diabetic rats].},
  author={Yiben Yu and Yimou Wu and Gebo Wen and Wenqiong Yang},
  journal={Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology},
  year={2014},
  volume={30 8},
  pages={793-7}
}
OBJECTIVE To investigate the effect of pioglitazone on the expression of Toll-like receptor 4 (TLR4) in renal tissue of diabetic rats. METHODS The male Sprague Dawlry rats (n=57) were randomly divided into the control group (n=9) and experimental group (n=48). The experimental rats were injected introperatoneally with 50 mg/kg streptozotocin (STZ) and the controls were given sodium citrate buffer instead. Then the experimental rats were randomized into five groups: pioglitazone 5 mg/(kg.d… CONTINUE READING