[Effect of phenytoin on neurotoxin homocysteine thiolactone-induced convulsions and epileptic status in rats with cobalt-induced epilepsy].

Abstract

The administration of neurotoxin thiolactone homocysteine in rats with cobalt-induced epileptogenic focus in the sensomotor cortical region led to the development of secondary generalized convulsions and epileptic state. The pattern was analogous to the manifestation of convulsions in epileptic state in humans. Fenitoin (50 mg/kg) inhibited the development… (More)

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Cite this paper

@article{Voronina2002EffectOP, title={[Effect of phenytoin on neurotoxin homocysteine thiolactone-induced convulsions and epileptic status in rats with cobalt-induced epilepsy].}, author={T. A. Voronina and M I Stoĭko and Lubov Nerobkova and G N Avakian and V. A. Kraineva}, journal={Eksperimental'naia i klinicheskaia farmakologiia}, year={2002}, volume={65 1}, pages={15-8} }