[Effect of p38 MAPK on elemene-induced cell cycle arrest in C6 glioblastoma cells].

@article{Yao2008EffectOP,
  title={[Effect of p38 MAPK on elemene-induced cell cycle arrest in C6 glioblastoma cells].},
  author={Yi-qun Yao and Ying-hui Xu and Jun Lu and Hong-yu Zhou and Yi-zheng Wang},
  journal={Zhonghua yi xue za zhi},
  year={2008},
  volume={88 1},
  pages={56-8}
}
OBJECTIVE To observe the effect of elemene on cell cycle of rat C6 glioblastoma cells. METHODS Cell cycle analysis and expression of p38 in C6 glioblastoma cells under elemene treatment were measured by flow cytometry and Western blot. Flow cytometry and MTT assay were used to examine cell cycle and cell proliferation while C6 glioblastoma cells were pretreated with p38 inhibitor and DN-p38 plasmids. RESULTS The fraction of C6 in the G0/G1 phase increased 11%, 6.95%, 19.57% respectively in… CONTINUE READING