[Effect of osteopontin silencing by lentivirus-mediated delivery of siRNA on glioma cell invasion and apoptosis].

@article{Yan2009EffectOO,
  title={[Effect of osteopontin silencing by lentivirus-mediated delivery of siRNA on glioma cell invasion and apoptosis].},
  author={Wei Yan and Chun-fa Qian and Lei Shi and Jin Qian and Zhen Ming Fu and Ning Liu and Ai-lin Lu and Yongping You},
  journal={Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics},
  year={2009},
  volume={26 5},
  pages={525-8}
}
OBJECTIVE To investigate the effect of osteopontin silencing on the invasion and apoptosis of U251 cells. METHODS The invasion, apoptosis and levels of uPA, MMP-2 and MMP-9 were determined by invasion assay, flow cytometry, Western blot and real-time fluorescence quantitative PCR respectively. RESULTS Osteopontin small interference RNA (siRNA) inhibited… CONTINUE READING