[Effect of mitoxantrone on proliferation and apoptosis of human multiple myeloma cell RPMI8226].

@article{Qi2014EffectOM,
  title={[Effect of mitoxantrone on proliferation and apoptosis of human multiple myeloma cell RPMI8226].},
  author={Mei-Ying Qi and Xin Liu and Bao-Lan Liu and Nai-Cen Zhou and Bo Xu},
  journal={Zhongguo shi yan xue ye xue za zhi},
  year={2014},
  volume={22 6},
  pages={1633-9}
}
This study was aimed to investigate the effects of mitoxantrone on proliferation and apoptosis of human multiple myeloma cell line RPMI-8226 and its mechanism. The inhibitory rate of RPMI8226 cells proliferation was assayed by MTT, the morphological changes of RPMI-8226 cells were observed by inverted flurescent microscopy and transmission electron microscopy, the apoptosis rate and the cell cycle distribution of RPMI-8226 cells were detected by flow cytometry. The effects of mitoxantrone on… CONTINUE READING