[Effect of maternal BDE-209 exposure on the expression of GAP-43 and BDNF in the hippocampus of the offspring rats].

@article{Jiang2008EffectOM,
  title={[Effect of maternal BDE-209 exposure on the expression of GAP-43 and BDNF in the hippocampus of the offspring rats].},
  author={Hui-ping Jiang and Yanhong Yu and Dun-jin Chen and Ying Wu and Bo Xu},
  journal={Nan fang yi ke da xue xue bao = Journal of Southern Medical University},
  year={2008},
  volume={28 8},
  pages={1319-22}
}
OBJECTIVE To evaluate the effect of prenatal and lactational exposure to brominated diphenyl ethers-209 (BDE-209) on the expression of growth associated protein-43 (GAP-43) and brain-derived neurotrophic factors (BDNF) in the hippocampus of the offspring rats. METHODS Peanut oil suspensions of commercial BDE-209 were administered daily at doses of 100, 300, 600, and 1200 mg/kg by oral gavage in pregnant Wistar rats (groups A, B, C, and D, respectively). The control group (E) only received… CONTINUE READING

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