Corpus ID: 26159035

[Effect of irradiation-induced pcDNA3.1-Egr.1p-p16 on cell apoptosis and cell cycle of JF305 cells].

@article{Ma2007EffectOI,
  title={[Effect of irradiation-induced pcDNA3.1-Egr.1p-p16 on cell apoptosis and cell cycle of JF305 cells].},
  author={Hong-bing Ma and Xijng Wang and Jie Ma and Hui Xia and Zheng Wang and Zhang-jun Li and Zhi-kai Han and Cong-mei Wu},
  journal={Nan fang yi ke da xue xue bao = Journal of Southern Medical University},
  year={2007},
  volume={27 8},
  pages={
          1183-6
        }
}
OBJECTIVE To observe the effect of pcDNA3.1-Egr.1p-p16 plasmid on apoptosis and cell cycle of pancreatic carcinoma JF305 cell line. METHODS JF305 cells were cultured and transfected with pcDNA3.1-Egr.1p-p16 plasmid via Lipofectamine(TM) 2000, followed by irradiation by 6MV-X at 4 Gy (dose rate 2.50 Gy/min). The cell cycle and cell apoptosis changes were analyzed by flow cytometry. RESULTS In cells infected with pcDNA3.1-Egr.1p-p16 plasmid and those with pcDNA3.1-Egr.1p-p16 plasmid infection… Expand
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