Corpus ID: 3122507

[Effect of humoral factors of the spleen of rats with acute and chronic toxic liver involvement on the physiologic and reparative regeneration of hepatocytes].

@article{Konoplia1991EffectOH,
  title={[Effect of humoral factors of the spleen of rats with acute and chronic toxic liver involvement on the physiologic and reparative regeneration of hepatocytes].},
  author={A I Konoplia and I A Shveĭnov and L G Prokopenko and E N Konoplia},
  journal={Patologicheskaia fiziologiia i eksperimental'naia terapiia},
  year={1991},
  volume={5},
  pages={
          30-2
        }
}
  • A I Konoplia, I A Shveĭnov, +1 author E N Konoplia
  • Published 1991
  • Medicine
  • Patologicheskaia fiziologiia i eksperimental'naia terapiia
  • It was demonstrated in experiments on Wistar rats with carbon tetrachloride induced acute and chronic affection of the liver that the supernatant of the splenic cells of the poisoned animals contains 2 undialyzable factors with a molecular mass of more than 150 and 10-12 kDa. The splenocytic substances stimulate hepatocyte proliferation both in healthy allogeneic recipients and under conditions of increased proliferative activity of hepatocytes in experimental pathology of the liver. 

    Topics from this paper