[Effect of geniposide on LPS-induced activation of TLR4-NF-κB pathway in RAW264.7 macrophage cell line].

@article{Huang2013EffectOG,
  title={[Effect of geniposide on LPS-induced activation of TLR4-NF-κB pathway in RAW264.7 macrophage cell line].},
  author={Lihua Huang and Chunjie Wang and Gaowa Naren and Gele Aori},
  journal={Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology},
  year={2013},
  volume={29 10},
  pages={1012-4}
}
OBJECTIVE To study the anti-inflammatory mechanism of geniposide and observe the effect of geniposide on the expression of Toll-like receptor 4 (TLR4), the activity of NF-κB, and the release of pro-inflammatory cytokines- TNF-α, IL-1, and IL-6-in the RAW264.7 macrophages treated with lipopolysaccharide (LPS). METHODS There were three experimental groups, including the control group, LPS group and LPS combined with geniposide group in this study. RAW264.7 macrophage cells were treated with LPS… CONTINUE READING