Corpus ID: 25172815

[Effect of emodin on NO-cGMP signal pathway in rat vascular endothelium in vitro].

@article{Wang2006EffectOE,
  title={[Effect of emodin on NO-cGMP signal pathway in rat vascular endothelium in vitro].},
  author={Wei-min Wang and Yan-qin Yu and Ling-Bo Qian},
  journal={Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine},
  year={2006},
  volume={26 7},
  pages={
          636-9
        }
}

Wei-min Wang, Yan-qin Yu, Ling-Bo Qian

Published 2006

Chemistry, Medicine

Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine

OBJECTIVE To investigate the vasorelaxation effect of emodin and its relationship with NO-cGMP signal pathway. METHODS Changes of tension of rat thoracic aortic rings were measured by MedLab biologic signal collection system, and the activity of total nitric oxide synthase (tNOS), constitutive NOS (cNOS) and inducible NOS (iNOS) in endothelium after being treated with emodin was determined with nitric acid reductase method. RESULTS Emodin relaxed the phenylephrine and potasium chlorate… CONTINUE READING

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