[Effect of cryotherapy and 5-fluorouracil on apoptosis of G422 glioma cells].

@article{Wang2004EffectOC,
  title={[Effect of cryotherapy and 5-fluorouracil on apoptosis of G422 glioma cells].},
  author={Hui Wang and H Tu and Jun Qin and Xin-jian Li and Kuan-Ming Huang and Zhang-ming Zhou and Lun-Chang Wang},
  journal={Ai zheng = Aizheng = Chinese journal of cancer},
  year={2004},
  volume={23 4},
  pages={412-5}
}
BACKGROUND & OBJECTIVE It was unknown whether the combination of cryotherapy and 5-fluorouracil (5-FU) could produce a synergistic effect, though both of them could induce apoptosis of glioma cells. The aim of this study was to observe the effect of cryotherapy and 5-fluorouracil on apoptosis of G422 glioma cells and to investigate the potential mechanism. METHODS (1)Experimental mice models with G422 glioma were established. Cryotherapy (-180 degrees C,90s),chemotherapy (5-FU, 18 mg/kg), and… CONTINUE READING