[Effect of adriamycin on expression of mdr1 gene in guinea pig cochlea lateral wall].

OBJECTIVE To study whether ADM affect the expression of mdr1 gene in guinea pig cochlea lateral wall. METHOD Sixty white guinea pigs with red eyes were divided into three groups: control group, NS group and ADM group. Guinea pigs were administered an intravenous injection of 30 mg/kg ADM. Four hoars later,ten animals were then immediately sacrificed, and… CONTINUE READING