• Corpus ID: 59412428

[Effect of Simiao Yong'an Decoction on the Expression of Wnt/p-catenin Signaling Pathway in Diabetic Ulcer Model Rats].

@article{YaNan2017EffectOS,
  title={[Effect of Simiao Yong'an Decoction on the Expression of Wnt/p-catenin Signaling Pathway in Diabetic Ulcer Model Rats].},
  author={Zhao Ya-Nan and Ming Liu and Yue Zhang and Bin Wang and Yu-dong Zhang and Qingli Hao and Jian-liang Wei},
  journal={Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine},
  year={2017},
  volume={37 1},
  pages={
          79-85
        }
}
  • Zhao Ya-Nan, Ming Liu, +4 authors Jian-liang Wei
  • Published 2017
  • Medicine
  • Zhongguo Zhong xi yi jie he za zhi Zhongguo Zhongxiyi jiehe zazhi = Chinese journal of integrated traditional and Western medicine
Objective To observe the changes of the Wnt/β-catenin signaling pathway in diabetic ulcer (DU) model rats and to study the effect of Simiao Yong'an Decoction (SYD) on it. Methods Totally 51 female Wistar rats were divided into the normal control group (n =17) and the diabetes mellitus (DM) group (n =34) according to random digit table. Rats in the normal control group were fed with common forage. Those in the DM group were prepared for DM model by high fat high glucose forage +intrap- eritoneal… 
1 Citations
The signaling pathways of traditional Chinese medicine in promoting diabetic wound healing.
  • Xin Zhou, Yanling Guo, Kun Yang, Peng Liu, Jun Wang
  • Medicine
    Journal of ethnopharmacology
  • 2021
TLDR
TCM could regulate the signaling pathways to promote diabetic wound healing, such as Wnt, Nrf2/ARE, MAPK, PI3K/Akt, NF-κB, Notch, TGF-β1/Smad, HIF-1α/VEGF, which maintaining inflammatory interaction balance, inhibiting oxidative stress and regulating abnormal glucose metabolism.