[Effect of N-methyl-D-aspartate on the spontaneous activity generated by isolated spinal cord of 16 to 20-day-old chick embryos].

@article{Chub1991EffectON,
  title={[Effect of N-methyl-D-aspartate on the spontaneous activity generated by isolated spinal cord of 16 to 20-day-old chick embryos].},
  author={Nikolai Chub and Konstantin V. Baev},
  journal={Neirofiziologiia = Neurophysiology},
  year={1991},
  volume={23 2},
  pages={205-13}
}
Bath-application of N-methyl-D-aspartate (NMDA) and antagonist of NMDA-receptors 2-amino-5-phosphonovaleric acid (2-APV) has been studied from the standpoint of its effect on the spontaneous activity in dorsal and ventral roots (DR and VR, respectively) generated by isolated spinal cord of 16-20-day-old chick embryo. Spontaneous activity consisted of synchronous oscillations of electrotonic potentials in DR and VR. Bath-application of NMDA (2-25 mumol/l) increased amplitude of the electrotonic… CONTINUE READING

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