Corpus ID: 22343867

[Effect of 7-hydroxygluacine on brain biogenic monoamines].

  title={[Effect of 7-hydroxygluacine on brain biogenic monoamines].},
  author={V. D. Petkov and T. Grakhoska and E. Konstantinova and V. Petkov},
  journal={Farmakologiia i toksikologiia},
  volume={48 3},
  • V. D. Petkov, T. Grakhoska, +1 author V. Petkov
  • Published 1985
  • Chemistry, Medicine
  • Farmakologiia i toksikologiia
  • In experiments on male albino rats it was established that the aporphine alkaloid 7-hydroxyglaucine injected i.p. at a dose of 1/10 of the LD50 induced many changes in the brain level of biogenic amines. Serotonin content was significantly increased in all brain structures studied (whole brain. cortex, striatum, and hypothalamus) Dopamine level was increased in the whole brain and cortex and was decreased in the hypothalamus; noradrenaline level was increased in the cortex and was decreased in… CONTINUE READING