[Effect of 5-hydroxymethyl furfural on BCL-2 and NF-kappaB gene expression of apoptotic rat hippocampal neurons injured by H2O2].

@article{Gu2011EffectO5,
  title={[Effect of 5-hydroxymethyl furfural on BCL-2 and NF-kappaB gene expression of apoptotic rat hippocampal neurons injured by H2O2].},
  author={Hai Xia Gu and Ya-Bing Jiang and Hai-ying Jiang and Dong-qing Xu and Jing-Ting Yu and Xia Ding and Feng-ming Zhao and Z. W. Zhan and M Wang},
  journal={Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials},
  year={2011},
  volume={34 11},
  pages={1753-6}
}
OBJECTIVE To investigate the effect of 5-hydroxymethyl furfural (5-HMF) on apoptosis and BCL-2, NF-kappaB gene expression of rat hippocampal neurons injured by hydroperoxide (H2O2). METHODS Hippocampal neurons of newly born rat were cultured in vivo and injured by H2O2. Effect of different concentration of 5-HMF on cell viability was measured by MTT. Flow cytometer (FCM) was used to measure the apoptosis of rat hippocampal neurons pre-cultured with different concentration of 5-HMF,Western… CONTINUE READING