[Effect of 2-phenoxyethanol on potency of Sabin inactivated poliomyelitis vaccine and its safety].

@article{Bian2007EffectO2,
  title={[Effect of 2-phenoxyethanol on potency of Sabin inactivated poliomyelitis vaccine and its safety].},
  author={Chuan-xiu Bian and Shu-de Jiang and Jian-Yong Yang and Ming-bo Sun and Ming-xue Xie and Xin-wen Zhang and Guo-yang Liao and Weidong Li},
  journal={Zhonghua shi yan he lin chuang bing du xue za zhi = Zhonghua shiyan he linchuang bingduxue zazhi = Chinese journal of experimental and clinical virology},
  year={2007},
  volume={21 1},
  pages={44-6}
}
OBJECTIVE To investigate the effect of 2-phenoxyethanol on potency of Sabin inactivated poliomyelitis vaccine (IPV). METHODS Sabin IPV samples containing 5 mg or 7 mg 2-phenoxyethanol each dosage respectively were placed separately at 4 degrees C, 37 degrees C for 2 days and 7 days. D-antigen contents were tested with ELISA method. Then neutralizing antibodies in mice and guinea pigs were detected. The safety experiment was performed according to unusual toxicity test of China requirement for… CONTINUE READING

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