[Effect and mechanism of inhibition of lipopolysaccharide-induced pulmonary fibrosis by butyric acid].

OBJECTIVE To evaluate the inhibitory effect of butyric acid (BA) as a histone deacetylase (HDAC) inhibitor on lipopolysaccharide (LPS)-induced pulmonary fibrosis and its mechanism. METHODS Thirty C57/BL6 mice were randomly divided into three groups according to the random number method, namely control group (physiological saline was given… CONTINUE READING