[Dynamics of the change in Na, K-ATPase activity during the development of isoproterenol-induced myocardial necrosis in rats].


Na, K-ATPase activity of heart tissue homogenates was found to be depressed 6 and 24 h after the last injection of isoproterenol to rats (100 mg/kg s. c. daily for 2 consecutive days) whereas after 1 h it was essentially unchanged. The extent of the reduction in the enzyme activity was virtually the same both 6 and 24 h after myocardial necrosis induction… (More)


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