[Dynamic evolution of MMP-2 gene expression and its enzymatic activities in experimental liver fibrosis].

Abstract

OBJECTIVES To explore the dynamic changes and interactions between MMP-2 and TIMP-2 during experimental liver fibrosis. METHODS Wistar rats were randomly allocated into a normal group and a model group. To induce liver fibrosis, rats were injected intraperitoneally with dimethylnitrosamine (DMN) three consecutive times in the first week, then two… (More)

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