[Dopamine D2 and D4 receptor genes distinguish the clinical presence of tics in obsessive-compulsive disorder].

@article{Nicolini1998DopamineDA,
  title={[Dopamine D2 and D4 receptor genes distinguish the clinical presence of tics in obsessive-compulsive disorder].},
  author={Humberto Nicolini and C. Cruz and Francisco P{\'a}ez and Beatriz Camarena},
  journal={Gaceta medica de Mexico},
  year={1998},
  volume={134 5},
  pages={521-7}
}
An allelic association study between dopamine receptor gene polymorphisms D2 (DRD2) and D4 (DRD4), in obsessive-compulsive patients (OCD) with or without chronic motor or vocal tics (OCD+ or OCD-) was performed. Molecular genotypes were obtained using the polymerase chain reaction method (PCR) in 66 patients diagnosed according DSMIV criteria, 12/66 OCD… CONTINUE READING