[Distribution and accumulation of antibiotics in cells and tissues and toxicity studies by immunocytochemistry].

  • Kunio Fujiwara
  • Published 2011 in
    Yakugaku zasshi : Journal of the Pharmaceutical…


No true immunocytochemistry (ICC) for drugs nor its application to pharmacokinetic studies is available. Recently, our studies have shown that ICC for drugs is extremely useful for such studies by utilizing easy and safe techniques, and gives direct evidence of drug localization. We have therefore developed antibodies and a series of pretreatment conditions… (More)