[Dilated cardiomyopathy as a genetic disease: molecular and clinical aspects].

@article{Frey2008DilatedCA,
  title={[Dilated cardiomyopathy as a genetic disease: molecular and clinical aspects].},
  author={Norbert Frey and Hugo A. Katus},
  journal={Der Internist},
  year={2008},
  volume={49 1},
  pages={43-50}
}
Dilated cardiomyopathy is a disease of heterogenous etiology. In up to 50% of cases, familial aggregation is observed. During the past decade, several DCM-causing mutations could be identified, several of these in sarcomeric proteins. A specific component of the sarcomere, the z-disc, appears to be a "hot spot" in the molecular pathogenesis of DCM. Yet… CONTINUE READING